{"id":32741,"date":"2019-11-30T22:47:47","date_gmt":"2019-11-30T21:47:47","guid":{"rendered":"https:\/\/www.buchinger-wilhelmi.com\/?p=32741"},"modified":"2023-06-09T09:00:25","modified_gmt":"2023-06-09T07:00:25","slug":"microbiome-study","status":"publish","type":"post","link":"https:\/\/www.buchinger-wilhelmi.com\/es\/microbiome-study\/","title":{"rendered":"Estudio sobre el ayuno: efecto del ayuno Buchinger Wilhelmi en la composici\u00f3n de las bacterias intestinales"},"content":{"rendered":"<div class=\"wpb-content-wrapper\">[vc_row][vc_column][vc_column_text]\r\n<h3 class=\"wp-block-heading\">Efecto de un ayuno de diez d\u00edas, seg\u00fan el Programa Buchinger Wilhelmi, en la composici\u00f3n de las bacterias intestinales: estudio en quince varones sanos.<\/h3>\r\n\r\n<p>La colonizaci\u00f3n bacteriana del intestino desempe\u00f1a un papel importante en el mantenimiento de la salud de las personas. En el presente estudio se examinan los efectos de un ayuno peri\u00f3dico de 10 d\u00edas bajo supervisi\u00f3n m\u00e9dica, seg\u00fan el Programa Buchinger Wilhelmi, en la composici\u00f3n de las bacterias intestinales y los par\u00e1metros inmunomoduladores en 15 varones sanos. Se ha comprobado que el ayuno modifica de forma reversible la composici\u00f3n de las bacterias intestinales en individuos sanos. Aunque la eficacia y seguridad del Programa Buchinger Wilhelmi se hab\u00eda demostrado recientemente en un estudio en el que participaron 1.422 voluntarios, el estudio actual constituye una base importante para nuevas investigaciones sobre los efectos del ayuno en el microbioma de las personas enfermas.<\/p>\r\n<h3>\u00a0<\/h3>\r\n<h3>Resultados del estudio publicado en el Journal of Nutritional Sciences:<\/h3>\r\n<ul>\r\n<li>Junto con el \u00abcambio metab\u00f3lico\u00bb se produjo tambi\u00e9n un cambio en la composici\u00f3n de las bacterias intestinales. De un lado, disminuy\u00f3 el n\u00famero de cepas bacterianas que intervienen en el metabolismo de los carbohidratos y los alimentos (por ejemplo, Lachnospiraceae y Ruminococcaceae), mientras que, de otro, se comprob\u00f3 un aumento de las cepas que obtienen energ\u00eda del metabolismo de los sustratos end\u00f3genos (como Bacteroides y Proteobacterias) con una inversi\u00f3n de la relaci\u00f3n Bacteroides:Firmicutes.<\/li>\r\n<li>En el marco de la s\u00edntesis de los alimentos se produjo un aumento de las prote\u00ednas inmunomoduladoras (citoquinas IL-6, IL-10, TNF-\u03b1, IFN-\u03b3) en sangre como indicio de una reactivaci\u00f3n de la respuesta inmunitaria tras la reintroducci\u00f3n de alimentos s\u00f3lidos.<\/li>\r\n<li>Tres meses despu\u00e9s del ayuno, la composici\u00f3n de las bacterias intestinales era de nuevo la misma que antes del ayuno. La detecci\u00f3n de un aumento de \u00e1cidos grasos de cadena corta en las heces puede considerarse un efecto positivo del ayuno, ya que protegen la mucosa del colon.<\/li>\r\n<li>En el contexto de los cambios metab\u00f3licos t\u00edpicos del ayuno peri\u00f3dico seg\u00fan el Programa Buchinger Wilhelmi \u2013uso de \u00e1cidos grasos y cuerpos cet\u00f3nicos en lugar de carbohidratos como principales proveedores de energ\u00eda\u2013, mejoraron par\u00e1metros metab\u00f3licos como el peso corporal, la circunferencia abdominal, la presi\u00f3n arterial y el colesterol. El bienestar emocional y f\u00edsico tambi\u00e9n mejor\u00f3 durante el ayuno.<\/li>\r\n<\/ul>\r\n\r\n<p>Mesnage, R., Grundler, F., Schwiertz, A., Le Maho, Y., &amp; Wilhelmi de Toledo, F. (2019). Changes in human gut microbiota composition are linked to the energy metabolic switch during 10 d of Buchinger fasting. Journal of Nutritional Science, 8, E36. doi:10.1017\/jns.2019.33<br \/>Wilhelmi de Toledo, F., Grundler, F., Bergouignan, A., Drinda, S., &amp; Michalsen, A. (2019). Safety, health improvement and well-being during a 4 to 21-day fasting period in an observational study including 1422 subjects. PLoS One, 14(01).<\/p>\r\n<p class=\"wp-block-paragraph\">&nbsp;<\/p>\r\n\r\n<p>Contactos:<\/p>\r\n<p class=\"wp-block-paragraph\">Dra. Fran\u00e7oise Wilhelmi de Toledo<br \/>E-Mail: <a href=\"mailto:francoise.wilhelmi@buchinger-wilhelmi.com\" target=\"_blank\" rel=\"noreferrer noopener\" aria-label=\"undefined (opens in a new tab)\">francoise.wilhelmi@buchinger-wilhelmi.com<\/a><\/p>\r\n<p>Dr. Robin Mesnage<br \/>E-Mail: <a href=\"mailto:robin.mesnage@buchinger-wilhelmi.com\">robin.mesnage@buchinger-wilhelmi.com<\/a><\/p>\r\n\r\n<p>&nbsp;<\/p>\r\n[\/vc_column_text][\/vc_column][\/vc_row]<\/div>","protected":false},"excerpt":{"rendered":"<p>Efecto de un ayuno de diez d\u00edas, seg\u00fan el Programa Buchinger Wilhelmi, en la composici\u00f3n de las bacterias intestinales: estudio en quince varones sanos<\/p>\n","protected":false},"author":30,"featured_media":32343,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_custom_body_class":"","_custom_post_class":"","_searchwp_excluded":"","inline_featured_image":false,"footnotes":""},"categories":[79,187,156],"tags":[],"class_list":["post-32741","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-news","category-fasten-studien-es","category-notas-de-prensa"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v23.8 - 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