{"id":43389,"date":"2021-11-10T13:12:37","date_gmt":"2021-11-10T12:12:37","guid":{"rendered":"https:\/\/www.buchinger-wilhelmi.com\/?p=43389"},"modified":"2021-12-17T15:23:37","modified_gmt":"2021-12-17T14:23:37","slug":"fonte-musculaire-degradation-proteines-jeune-long-terme-etude","status":"publish","type":"post","link":"https:\/\/www.buchinger-wilhelmi.com\/fr\/fonte-musculaire-degradation-proteines-jeune-long-terme-etude\/","title":{"rendered":"La d\u00e9gradation du muscle et des prot\u00e9ines joue-t-elle un r\u00f4le significatif chez l\u2019homme en bonne sant\u00e9 pendant le je\u00fbne prolong\u00e9 ?"},"content":{"rendered":"
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\n\t\n\t\t\t

\n\t\t\tLa derni\u00e8re \u00e9tude publi\u00e9e sur le je\u00fbne et la musculature :\t\t<\/p>\n\t\n\t\n\t

\n\t\tLa d\u00e9gradation du muscle et des prot\u00e9ines joue-t-elle un r\u00f4le significatif chez l\u2019homme en bonne sant\u00e9 pendant le je\u00fbne prolong\u00e9 ?\t<\/h2>\n\n\t\n\t\t\n<\/div>[\/vc_column][\/vc_row][vc_row css=\u00a0\u00bb.vc_custom_1637309103630{margin-bottom: 30px !important;padding-top: 20px !important;}\u00a0\u00bb][vc_column][vc_column_text]\n

Une \u00e9tude prospective sur l\u2019adaptation physiologique au je\u00fbne<\/h4>\n[\/vc_column_text][\/vc_column][\/vc_row][vc_row css=\u00a0\u00bb.vc_custom_1633441047016{margin-bottom: 30px !important;}\u00a0\u00bb][vc_column][vc_column_text]\u00dcberlingen, le 10\/11\/2021 \u2013 16 hommes en bonne sant\u00e9 et ne pr\u00e9sentant pas d\u2019ob\u00e9sit\u00e9 ont je\u00fbn\u00e9 pendant 10 jours, selon le programme des cliniques Buchinger Wilhelmi. Le protocole impliquait la prise quotidienne d\u2019un suppl\u00e9ment sans prot\u00e9ines de 200 \u00e0 250 kcal\/jour, sous forme de jus de fruits et de bouillons de l\u00e9gumes ainsi qu\u2019un programme d\u2019exercice mod\u00e9r\u00e9 de trois heures par jour.<\/strong>[\/vc_column_text][\/vc_column][\/vc_row][vc_row css=\u00a0\u00bb.vc_custom_1633441823106{margin-bottom: 30px !important;}\u00a0\u00bb][vc_column][vc_column_text]La perte de poids de 5,9 \u00b1 0,2 kg en moyenne r\u00e9sulte \u00e0 40 % de la d\u00e9gradation des graisses, \u00e0 25 % de celle des prot\u00e9ines issues de tissus m\u00e9taboliquement actifs : foie, reins, rate, muqueuse intestinale, c\u0153ur, muscles squelettiques, \u00e0 8 % du glycog\u00e8ne h\u00e9patique et musculaire et \u00e0 27 % de l\u2019\u00e9limination d\u2019eau. Des m\u00e9canismes d\u2019\u00e9pargne de prot\u00e9ines se mettent en place rapidement.[\/vc_column_text][\/vc_column][\/vc_row][vc_row content_placement=\u00a0\u00bbmiddle\u00a0\u00bb css=\u00a0\u00bb.vc_custom_1633444423520{padding-left: 20px !important;background-color: #ededed !important;}\u00a0\u00bb][vc_column width=\u00a0\u00bb1\/2″][vc_column_text]L’\u00e9tude a permis de d\u00e9montrer que l\u2019implication des muscles est moins importante qu\u2019on ne l\u2019a cru pendant des d\u00e9cennies, et qu\u2019\u00e0 l\u2019instar des autres organes, la musculature se r\u00e9g\u00e9n\u00e8re apr\u00e8s le je\u00fbne.<\/p>\n

Non seulement il n\u2019y a pas de \u00ab fonte musculaire \u00bb, mais la performance des muscles des extr\u00e9mit\u00e9s inf\u00e9rieures s\u2019am\u00e9liore au contraire nettement apr\u00e8s le je\u00fbne, tandis que celle des autres muscles se maintient.[\/vc_column_text][\/vc_column][vc_column width=\u00a0\u00bb1\/2″][vc_single_image image=\u00a0\u00bb43522″ img_size=\u00a0\u00bblarge\u00a0\u00bb alignment=\u00a0\u00bbright\u00a0\u00bb onclick=\u00a0\u00bbcustom_link\u00a0\u00bb img_link_target=\u00a0\u00bb_blank\u00a0\u00bb css_animation=\u00a0\u00bbfadeIn\u00a0\u00bb link=\u00a0\u00bbhttps:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/jcsm.12766″][\/vc_column][\/vc_row][vc_row css=\u00a0\u00bb.vc_custom_1637316031616{margin-top: 20px !important;margin-bottom: 30px !important;}\u00a0\u00bb][vc_column]

\n\n\t\n\n\t\t\n\t\t\n\t\t\tLire l'article en entier\t\t<\/span>\n\n\t\t\n\t\t\t<\/a>\n\n<\/div>[\/vc_column][\/vc_row][vc_row css=\u00a0\u00bb.vc_custom_1633441686538{margin-top: 30px !important;}\u00a0\u00bb][vc_column][vc_column_text]La d\u00e9gradation des prot\u00e9ines diminue de jour en jour<\/strong><\/p>\n

La d\u00e9gradation des prot\u00e9ines, document\u00e9e par le bilan azot\u00e9 n\u00e9gatif, diminue de jour en jour, gr\u00e2ce au d\u00e9clenchement de m\u00e9canismes d\u2019\u00e9pargne prot\u00e9ique. Un marqueur de la d\u00e9gradation des prot\u00e9ines musculaires, la 3-m\u00e9thylhistidine, s\u2019abaisse en effet d\u00e8s le 5e jour de je\u00fbne. D\u2019autres marqueurs de prot\u00e9olyse, dont la GOT et la cr\u00e9atinine, viennent confirmer cette observation. Apr\u00e8s le je\u00fbne, la myostatine diminue de mani\u00e8re significative, favorisant par-l\u00e0 la reconstitution de la masse musculaire.[\/vc_column_text][\/vc_column][\/vc_row][vc_row css=\u00a0\u00bb.vc_custom_1633441686538{margin-top: 30px !important;}\u00a0\u00bb][vc_column][vc_column_text]Observations apr\u00e8s un programme de je\u00fbne de 3 mois<\/strong><\/p>\n

Un nouvel examen fut effectu\u00e9 trois mois apr\u00e8s le je\u00fbne. L\u2019\u00e9tat g\u00e9n\u00e9ral des sujets \u00e9tait bon. Le poids corporel \u00e9tait plus bas qu\u2019en d\u00e9but de je\u00fbne et le m\u00e9tabolisme de base avait \u00e9galement diminu\u00e9 en cons\u00e9quence. Les valeurs qui avaient temporairement augment\u00e9 \u00e0 cause du je\u00fbne \u00e9taient revenues \u00e0 leur niveau initial.[\/vc_column_text][\/vc_column][\/vc_row][vc_row css=\u00a0\u00bb.vc_custom_1639644231206{margin-top: 30px !important;margin-bottom: 30px !important;}\u00a0\u00bb][vc_column][vc_video link=\u00a0\u00bbhttps:\/\/www.youtube.com\/watch?v=873gQ33G-6U\u00a0\u00bb][vc_empty_space height=\u00a0\u00bb50″][\/vc_column][\/vc_row][vc_row css=\u00a0\u00bb.vc_custom_1633441686538{margin-top: 30px !important;}\u00a0\u00bb][vc_column][vc_column_text]Plus d’\u00e9tudes sur le je\u00fbne<\/strong><\/p>\n

Comme document\u00e9 dans de pr\u00e9c\u00e9dentes publications, le programme de je\u00fbne des cliniques Buchinger Wilhelmi \u2013 avec activit\u00e9 physique \u2013 est une approche s\u00fbre pour pr\u00e9venir et traiter les maladies li\u00e9es \u00e0 l\u2019\u00e2ge (ob\u00e9sit\u00e9, diab\u00e8te de type 2 et autres troubles m\u00e9taboliques), ainsi que les maladies chroniques inflammatoires et le stress oxydatif. Il est n\u00e9anmoins indiqu\u00e9 pour les personnes d\u2019un \u00e2ge avanc\u00e9, souffrant d\u2019une insuffisance pond\u00e9rale et d\u2019une perte musculaire d\u00e9g\u00e9n\u00e9rative, de mettre en place d\u2019autres strat\u00e9gies nutritionnelles, pour autant que ces derni\u00e8res se r\u00e9v\u00e8lent n\u00e9cessaires d\u2019un point de vue th\u00e9rapeutique.<\/p>\n

D\u2019autres \u00e9tudes sont en cours pour \u00e9valuer dans quelle proportion les diff\u00e9rents tissus m\u00e9taboliquement actifs cit\u00e9s plus haut sont impliqu\u00e9s dans la d\u00e9gradation des prot\u00e9ines induite par le je\u00fbne et \u00e0 quelle vitesse ils se r\u00e9g\u00e9n\u00e8rent \u00e0 partir de cellules souches et de nouvelles synth\u00e8ses lors de la reprise alimentaire.[\/vc_column_text][\/vc_column][\/vc_row][vc_row css=\u00a0\u00bb.vc_custom_1633441686538{margin-top: 30px !important;}\u00a0\u00bb][vc_column][vc_column_text]Auteurs<\/strong><\/p>\n

Claire Laurens, Franziska Grundler, Anthony Damiot, Isabelle Chery, Anne-Laure Le Maho, Alexandre Zahariev, Yvon Le Maho, Audrey Bergouignan, Guillemette Gauquelin-Koch, Chantal Simon, St\u00e9phane Blanc, Fran\u00e7oise Wilhelmi de Toledo, <\/em><\/p>\n

\u00ab Is muscle and protein loss relevant in long-term fasting in healthy men? A prospective trial on physiological adaptations \u00bb, paru le 20 octobre 2021 dans Journal of Cachexia, Sarcopenia and Muscle<\/em>
\ndoi: 10.1002\/jcsm.12766<\/em><\/p>\n

Contact<\/strong>
\nDre Fran\u00e7oise Wilhelmi de Toledo
\nE-mail : francoise.wilhelmi@buchinger-wilhelmi.com<\/a>[\/vc_column_text][\/vc_column][\/vc_row][vc_row css=\u00a0\u00bb.vc_custom_1633454847795{margin-top: 30px !important;}\u00a0\u00bb][vc_column]

\n\n\t\n\n\t\t\n\t\t\n\t\t\tAutres \u00e9tudes, publications et litt\u00e9rature\t\t<\/span>\n\n\t\t\n\t\t\t<\/a>\n\n<\/div>[\/vc_column][\/vc_row]\n<\/div>","protected":false},"excerpt":{"rendered":"

[vc_row][vc_column][\/vc_column][\/vc_row][vc_row css=\u00a0\u00bb.vc_custom_1637309103630{margin-bottom: 30px !important;padding-top: 20px !important;}\u00a0\u00bb][vc_column][vc_column_text] Une \u00e9tude prospective sur l\u2019adaptation physiologique au je\u00fbne…<\/p>\n","protected":false},"author":30,"featured_media":43522,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_custom_body_class":"","_custom_post_class":"","_searchwp_excluded":"","inline_featured_image":false,"footnotes":""},"categories":[106,155,185],"tags":[],"class_list":["post-43389","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-news","category-communiques-de-presse","category-fasten-studien-fr"],"acf":[],"yoast_head":"\nLa d\u00e9gradation du muscle et des prot\u00e9ines joue-t-elle un r\u00f4le significatif chez l\u2019homme en bonne sant\u00e9 pendant le je\u00fbne prolong\u00e9 ? - BUCHINGER WILHELMI<\/title>\n<meta name=\"description\" content=\"Notre \u00e9tude nous a permis de d\u00e9montrer que l\u2019implication des muscles est vraisemblablement moins importante qu\u2019on ne l\u2019a cru pendant longtemps, et qu\u2019\u00e0 l\u2019instar des autres tissus organiques, la musculature se reconstruit apr\u00e8s le je\u00fbne.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.buchinger-wilhelmi.com\/fr\/fonte-musculaire-degradation-proteines-jeune-long-terme-etude\/\" \/>\n<meta property=\"og:locale\" content=\"fr_FR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"La d\u00e9gradation du muscle et des prot\u00e9ines joue-t-elle un r\u00f4le significatif chez l\u2019homme en bonne sant\u00e9 pendant le je\u00fbne prolong\u00e9 ? - BUCHINGER WILHELMI\" \/>\n<meta property=\"og:description\" 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